Creating dried, adsorbed samples will improve the separation performance on any cartridge. Biotage Samplet are designed for quick and convenient loading of concentrated samples.After the sample has been applied to the Samplet, the solvent is allowed to evaporate. The Samplet is then inserted into the Biotage Sfär Duo columns and you are ready to go.Samplets also are used as guard columns for Biotage Sfar C18, Biotage Sfar Bio C18 and Biotage Sfar Bio C4 columns.These Samplets are compatible with 5 to 12 gram columns and contain approximately 1.2 grams of Biotage ISOLUTE HM-N (diatomaceous earth) sorbent material. Shipped in packs of 20.